Opioid Crisis
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Fentanyl Reshapes US Drug Crisis, Shifting Public Concern Since 2015
WASHINGTON — 1,600 kilograms. That was the total amount of fentanyl used in healthcare globally in 2015, a figure that underscores the…
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Opioid Crisis Costs U.S. Over $1 Trillion Annually, Vaccine May Help
WASHINGTON, July 13 — The opioid crisis in the United States imposes an estimated economic cost of over $1 trillion annually, according…
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Preclinical Vaccine Neutralizes Fentanyl and 10 Analogs
HOUSTON, July 13 — A fentanyl vaccine candidate has moved one step closer to human testing, with preclinical results showing it blocked…
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Vaccinated mice show promise in blocking fentanyl’s deadly effects
WASHINGTON — Inside a laboratory, a small group of mice is changing how researchers think about the opioid crisis. These animals, immunized…
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Scripps Chemist Develops Vaccine To Train Immune System Against Fentanyl
LA JOLLA — Dr. Kim D. Janda is working on a vaccine that could change how the country fights the fentanyl crisis.…
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Vaccine blocks fentanyl from brain, clears animal trials
ISLAMABAD, July 13 — A vaccine candidate designed to block fentanyl from reaching the brain has completed preclinical studies in animals, with…
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Synthetic opioid crisis surges as fentanyl deaths more than double in five years
WASHINGTON, July 13 — The opioid crisis in the United States has reached unprecedented levels, with the Centers for Disease Control and…
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Clinical Timeline: Human Trials Expected to Begin Within Two Years
WASHINGTON, July 13 — A vaccine candidate designed to prevent fentanyl overdoses is moving toward human clinical trials, offering a potential new…
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Overdose deaths hit record high in 2021, fentanyl drives surge
WASHINGTON, July 13 — The opioid crisis in the United States has escalated dramatically over the past two decades, with synthetic opioids…
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University of Houston Fentanyl Vaccine Targets Drug’s Chemical Backbone
HOUSTON, July 13 — A novel vaccine candidate developed at the University of Houston is targeting the chemical backbone of fentanyl and…
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“UH Researchers Develop Fentanyl Vaccine to Combat Rising Overdoses”
HOUSTON, July 13 — A team of researchers at the University of Houston is developing a vaccine candidate designed to target fentanyl,…
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Next Steps From Preclinical to Human Trials Expected to Take Years
WASHINGTON, July 13 — The figure that matters for a potential breakthrough in the opioid crisis is 10 to 15 years. That…
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Novel vaccine trains immune system to neutralize fentanyl
HOUSTON, July 13 — On the ground in the fight against the opioid crisis, researchers at the University of Houston and the…
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Vertex’s New Painkiller Targets Nerves Without Opioid Risks
Vertex Pharmaceuticals is awaiting a regulatory decision on suzetrigine, a non-opioid analgesic designed for moderate to severe acute pain. The drug, which…
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New Medication Journavx Offers Hope for Acute Pain Relief Without Opioids
As of January 28, 2025, a novel oral medication for moderate to severe acute pain is approaching clinical availability. Suzetrigine, to be…
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CDC Tracks Three Deadly Waves of the US Opioid Crisis
The Centers for Disease Control and Prevention (CDC) has documented the evolution of America’s opioid epidemic in three successive waves, each characterized…
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U.S. Opioid Crisis Continues with Three Distinct Waves
The United States continues to confront an opioid crisis that public‑health officials rank among the most severe of recent times. Data from…
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